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Increased genomic alteration complexity and telomere shortening in B-CLL cells resistant to radiation-induced apoptosis
B-cell chronic lymphocytic leukemia (B-CLL) results in an accumulation of mature CD5(+)/CD23(+) B cells due to an uncharacterized defect in apoptotic cell death. B-CLL is not characterized by a unique recurrent genomic alteration but rather by genomic instability giving rise frequently to several ch...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
S. Karger AG
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813806/ https://ncbi.nlm.nih.gov/pubmed/19188704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000167821 |
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