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CD4 T cell subsets in the Mucosa are CD28(+)Ki-67(−)HLA-DR(−)CD69(+) but show differential infection based on α4β7 receptor expression during acute SIV infection
BACKGROUND: CD4 T cell depletion in the mucosa has been well documented during acute HIV and SIV infections. The demonstration the HIV/SIV can use the α4β7 receptor for viral entry suggests that these viruses selectively target CD4 T cells in the mucosa that express high levels of α4β7 receptor. MET...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813512/ https://ncbi.nlm.nih.gov/pubmed/19863675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0684.2009.00372.x |
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