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CD4 T cell subsets in the Mucosa are CD28(+)Ki-67(−)HLA-DR(−)CD69(+) but show differential infection based on α4β7 receptor expression during acute SIV infection

BACKGROUND: CD4 T cell depletion in the mucosa has been well documented during acute HIV and SIV infections. The demonstration the HIV/SIV can use the α4β7 receptor for viral entry suggests that these viruses selectively target CD4 T cells in the mucosa that express high levels of α4β7 receptor. MET...

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Bibliografiske detaljer
Main Authors: Kader, Muhamuda, Bixler, Sandra, Roederer, Mario, Veazey, Ronald, Mattapallil, Joseph J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813512/
https://ncbi.nlm.nih.gov/pubmed/19863675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0684.2009.00372.x
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