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Differential K(ATP) channel pharmacology in intact mouse heart

BACKGROUND: Classically, cardiac sarcolemmal K(ATP) channels have been thought to be composed of Kir6.2 (KCNJ11) and SUR2A (ABCC9) subunits. However, the evidence is strong that SUR1 (sulfonylurea receptor type 1, ABCC8) subunits are also expressed in the heart and that they play a significant funct...

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Main Authors: Glukhov, Alexey V., Flagg, Thomas P., Fedorov, Vadim V., Efimov, Igor R., Nichols, Colin G.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813353/
https://ncbi.nlm.nih.gov/pubmed/19744493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.08.026
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