Alternative Splicing and Extensive RNA Editing of Human TPH2 Transcripts

Brain serotonin (5-HT) neurotransmission plays a key role in the regulation of mood and has been implicated in a variety of neuropsychiatric conditions. Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the biosynthesis of 5-HT. Recently, we discovered a second TPH isoform (TPH2) in verteb...

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Main Authors: Grohmann, Maik, Hammer, Paul, Walther, Maria, Paulmann, Nils, Büttner, Andreas, Eisenmenger, Wolfgang, Baghai, Thomas C., Schüle, Cornelius, Rupprecht, Rainer, Bader, Michael, Bondy, Brigitta, Zill, Peter, Priller, Josef, Walther, Diego J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813293/
https://ncbi.nlm.nih.gov/pubmed/20126463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008956
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