Cytomegalovirus-Specific T Cells Persist at Very High Levels during Long-Term Antiretroviral Treatment of HIV Disease

BACKGROUND: In healthy, HIV seronegative, CMV seropositive adults, a large proportion of T cells are CMV-specific. High-level CMV-specific T cell responses are associated with accelerated immunologic aging (“immunosenesence”) in the elderly population. The impact of untreated and treated HIV infecti...

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Bibliographische Detailangaben
Hauptverfasser: Naeger, David M., Martin, Jeffrey N., Sinclair, Elizabeth, Hunt, Peter W., Bangsberg, David R., Hecht, Frederick, Hsue, Priscilla, McCune, Joseph M., Deeks, Steven G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813282/
https://ncbi.nlm.nih.gov/pubmed/20126452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008886
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