In Vivo CD8+ T-Cell Suppression of SIV Viremia Is Not Mediated by CTL Clearance of Productively Infected Cells

The CD8+ T-cell is a key mediator of antiviral immunity, potentially contributing to control of pathogenic lentiviral infection through both innate and adaptive mechanisms. We studied viral dynamics during antiretroviral treatment of simian immunodeficiency virus (SIV) infected rhesus macaques follo...

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Detalhes bibliográficos
Main Authors: Wong, Joseph K., Strain, Matthew C., Porrata, Rodin, Reay, Elizabeth, Sankaran-Walters, Sumathi, Ignacio, Caroline C., Russell, Theresa, Pillai, Satish K., Looney, David J., Dandekar, Satya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813272/
https://ncbi.nlm.nih.gov/pubmed/20126442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000748
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