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Recombination Rate and Selection Strength in HIV Intra-patient Evolution

The evolutionary dynamics of HIV during the chronic phase of infection is driven by the host immune response and by selective pressures exerted through drug treatment. To understand and model the evolution of HIV quantitatively, the parameters governing genetic diversification and the strength of se...

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Detalhes bibliográficos
Main Authors: Neher, Richard A., Leitner, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813257/
https://ncbi.nlm.nih.gov/pubmed/20126527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000660
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