Monoclonal immunoglobulin A antibodies directed against cholera toxin prevent the toxin-induced chloride secretory response and block toxin binding to intestinal epithelial cells in vitro.

Secretory immunoglobulin A (IgA) antibodies directed against cholera toxin (CT) are thought to be important in resistance to oral challenge with virulent Vibrio cholerae, although alternative mechanisms for protection of intestinal epithelia against CT-induced fluid secretion have been proposed. The...

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Bibliografiska uppgifter
Huvudupphovsmän: Apter, F M, Lencer, W I, Finkelstein, R A, Mekalanos, J J, Neutra, M R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1993
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC281311/
https://ncbi.nlm.nih.gov/pubmed/7693598
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