New model for analysis of mucosal immunity: intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholerae infection.

Secretory immunoglobulin A (sIgA) plays a role in defense against Vibrio cholerae and other microorganisms that infect mucosal surfaces, but it is not established whether sIgA alone can prevent disease. We report here a strategy for identifying the antigen specificities of monoclonal sIgA antibodies...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Winner, L, Mack, J, Weltzin, R, Mekalanos, J J, Kraehenbuhl, J P, Neutra, M R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258355/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1705246/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.3.977-982.1991
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