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Correlating measurements across samples improves accuracy of large-scale expression profile experiments

Gene expression profiling technologies suffer from poor reproducibility across replicate experiments. However, when analyzing large datasets, probe-level expression profile correlation can help identify flawed probes and lead to the construction of truer probe sets with improved reproducibility. We...

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Autors principals: Alvarez, Mariano Javier, Sumazin, Pavel, Rajbhandari, Presha, Califano, Andrea
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812950/
https://ncbi.nlm.nih.gov/pubmed/20042104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2009-10-12-r143
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