Interleukin-1 Beta Secretion is Activated Comparably by FliC and FljB Flagellins but Differentially by Wild-Type and DNA Adenine Methylase-Deficient Salmonella

Recognition of cytoplasmic bacterial flagellin by the Nod-like receptor ICE protease-activating factor (Ipaf) in macrophages leads to activation of caspase-1 and secretion of interleukin-1β (IL-1β). Salmonella possess two genes, fliC and fljB, that encode flagellin proteins. We examined the ability...

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Bibliographische Detailangaben
Hauptverfasser: Simon, Raphael, Samuel, Charles E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2008
Schlagworte:
Research Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812923/
https://ncbi.nlm.nih.gov/pubmed/18844581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2008.0022
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