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Interleukin-1 Beta Secretion is Activated Comparably by FliC and FljB Flagellins but Differentially by Wild-Type and DNA Adenine Methylase-Deficient Salmonella
Recognition of cytoplasmic bacterial flagellin by the Nod-like receptor ICE protease-activating factor (Ipaf) in macrophages leads to activation of caspase-1 and secretion of interleukin-1β (IL-1β). Salmonella possess two genes, fliC and fljB, that encode flagellin proteins. We examined the ability...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812923/ https://ncbi.nlm.nih.gov/pubmed/18844581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2008.0022 |
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