Alpha-2-macroglobulin functions as an inhibitor of fibrinolytic, clotting, and neutrophilic proteinases in sepsis: studies using a baboon model.

Alpha-2-macroglobulin (alpha 2M) may function as a proteinase inhibitor in vivo. Levels of this protein are decreased in sepsis, but the reason these levels are low is unknown. Therefore, we analyzed the behavior of alpha 2M in a baboon model for sepsis. Upon challenge with a lethal (4 baboons) or a...

Full description

Saved in:
Bibliographic Details
Main Authors: de Boer, J P, Creasey, A A, Chang, A, Abbink, J J, Roem, D, Eerenberg, A J, Hack, C E, Taylor, F B
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC281280/
https://ncbi.nlm.nih.gov/pubmed/7693593
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items