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Colitis-associated variant of TLR2 causes impaired mucosal repair due to TFF3 deficiency

BACKGROUND & AIMS: Goblet cells (GC) facilitate mucosal protection and epithelial barrier repair, yet the innate immune mechanisms that selectively drive GC functions have not been defined. The aim of this study was to determine whether TLR2 and modulation of GC-derived TFF3 are functionally lin...

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Detalhes bibliográficos
Main Authors: Podolsky, Daniel K., Gerken, Guido, Eyking, Annette, Cario, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812790/
https://ncbi.nlm.nih.gov/pubmed/19303021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.03.007
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