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A Sensitive Fluorescence-Based Assay for the Detection of ExoU-Mediated PLA(2) Activity

BACKGROUND: Pseudomonas aeruginosa is an opportunistic pathogen that causes disease in immunocompromised individuals, burn victims, and cystic fibrosis patients. Strains that secrete ExoU induce host cell lysis and damage epithelial tissue, which can lead to severe outcomes including sepsis and mort...

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Detalhes bibliográficos
Main Authors: Benson, Marc A., Schmalzer, Katherine M., Frank, Dara W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812683/
https://ncbi.nlm.nih.gov/pubmed/19900431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2009.10.025
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