ENHANCEMENT OF SPHINGOSINE KINASE 1 CATALYTIC ACTIVITY BY DELETION OF 21 AMINO ACIDS FROM THE COOH-TERMINUS*

Sphingosine kinase 1 (SphK1) responds to a variety of growth factor signals by increasing catalytic activity as it translocates to the plasma membrane (PM). Several studies have identified amino acids residues involved in translocation yet how SphK1 increases its catalytic activity remains to be elu...

Full description

Saved in:
Bibliographic Details
Main Authors: Hengst, Jeremy A., Guilford, Jacquelyn M., Conroy, Elizabeth J., Wang, Xujun, Yun, Jong K.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812673/
https://ncbi.nlm.nih.gov/pubmed/19914200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.11.006
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items