The Antiepileptic Drug Zonisamide Inhibits MAO-B and Attenuates MPTP Toxicity in Mice: Clinical Relevance

Zonisamide is an FDA-approved antiepileptic drug that blocks voltage-dependent Na(+) channels and T-type Ca(2+) channels and improves clinical outcome in Parkinson's disease (PD) patients when used as an adjunct to other PD therapies. Zonisamide also modifies dopamine (DA) activity, provides pr...

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Bibliographische Detailangaben
Hauptverfasser: Sonsalla, Patricia K., Wong, Lai-Yoong, Winnik, Bozena, Buckley, Brian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812670/
https://ncbi.nlm.nih.gov/pubmed/19948168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.11.018
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