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Zonisamide Increases Dopamine Turnover in the Striatum of Mice and Common Marmosets Treated With MPTP

Abstract.: The effect of zonisamide, an antiepileptic agent with anti-parkinsonian effects, was studied on dopamine neurons of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 mice and common marmosets. Groups of mice (n = 8 – 9) were treated with: MPTP (15 mg/kg every 2 h ×4); MPTP p...

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Detalhes bibliográficos
Principais autores: Hayato Yabe, Mohammed Emamussalehin Choudhury, Madoka Kubo, Noriko Nishikawa, Masahiro Nagai, Masahiro Nomoto
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2009-01-01
coleção:Journal of Pharmacological Sciences
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1347861319312149
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