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Glycogen synthase kinase 3 regulates PAX3-FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells

Patients with alveolar rhabdomyosarcoma (ARMS) have poorer response to conventional chemotherapy and lower survival rates than those with embryonal RMS (ERMS). To identify compounds that preferentially block the growth of ARMS, we conducted a small-scale screen of 160 kinase inhibitors against the A...

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Bibliographic Details
Main Authors: Zeng, Fu-Yue, Dong, Hanqing, Cui, Jimmy, Liu, Lingling, Chen, Taosheng
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812657/
https://ncbi.nlm.nih.gov/pubmed/19995556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.12.017
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