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Partitioning, dynamics, and orientation of lung surfactant peptide KL(4) in phospholipid bilayers
Lung surfactant protein B (SP-B) is a lipophilic protein critical to lung function at ambient pressure. KL(4) is a 21-residue peptide which has successfully replaced SP-B in clinical trials of synthetic lung surfactants. CD and FTIR measurements indicate KL(4) is helical in a lipid bilayer environme...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812611/ https://ncbi.nlm.nih.gov/pubmed/19735643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.08.020 |
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