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Partitioning, dynamics, and orientation of lung surfactant peptide KL(4) in phospholipid bilayers

Lung surfactant protein B (SP-B) is a lipophilic protein critical to lung function at ambient pressure. KL(4) is a 21-residue peptide which has successfully replaced SP-B in clinical trials of synthetic lung surfactants. CD and FTIR measurements indicate KL(4) is helical in a lipid bilayer environme...

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Autors principals: Long, Joanna R., Mills, Frank D., Ganesh, Omjoy K., Antharam, Vijay C., Farver, R. Suzanne
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812611/
https://ncbi.nlm.nih.gov/pubmed/19735643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.08.020
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