Gene therapy targeting Leiomyoma: Adenovirus mediated delivery of dominant negative estrogen receptor gene shrinks uterine tumors in Eker rat model

OBJECTIVE: To evaluate the utility of gene therapy for uterine fibroids in the Eker rat model using an adenovirus-mediated delivery of a dominant negative estrogen receptor gene (Ad-DN-ER). DESIGN: Animal study. SETTING: University animal laboratory. ANIMAL(S): 27 female Eker rats INTERVENTIONS: We...

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Autori principali: Hassan, Memy H, Salama, Salama A., Zhang, Dong, Arafa, Hossam M.M., Hamada, Farid M.A., Fouad, Hala, Walker, Cheryl C., Al-Hendy, Ayman
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812608/
https://ncbi.nlm.nih.gov/pubmed/19144333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2008.09.086
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