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Nitric Oxide and Thioredoxin Type 1 Modulate the Activity of Caspase 8 in HepG2 cells

Herein, we report that nitric oxide (NO) and the thioredoxin/thioredoxin reductase system affect the activity of caspase 8 in HepG2 cells. Exposure of cells to NO resulted in inhibition of caspase 8, while a subsequent incubation of the cells in NO-free medium resulted in spontaneous reactivation of...

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Autores principales: Sengupta, Rajib, Billiar, Timothy R., Kagan, Valerian E., Stoyanovsky, Detcho A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812598/
https://ncbi.nlm.nih.gov/pubmed/20005201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.12.036
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