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Synthesis and biological evaluation of nitric oxide-releasing derivatives of oleanolic acid as inhibitors of HepG2 cell apoptosis

A total of 106 nitric oxide-releasing derivatives of oleanolic acid were synthesized and their effects on the inhibition of anti-Fas-mediated HepG2 cell apoptosis were evaluated in vitro. Several compounds inhibited anti-Fas mediated HepG2 cell apoptosis in a dose-dependent manner. Within this serie...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chen, Li, Zhang, Yihua, Kong, Xiangwen, Peng, Sixun, Tian, Jide
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2007
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986654/
https://ncbi.nlm.nih.gov/pubmed/17446070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.03.068
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