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Reaction of human albumin with aspirin in vitro: mass spectrometric identification of acetylated lysines 199, 402, 519, and 545

The aspirin esterase activity of human plasma is due to butyrylcholinesterase and albumin. Our goal was to identify the amino acid residues involved in the aspirin esterase activity of albumin. Fatty acid free human albumin and human plasma were treated with aspirin for 5 min to 24 h. Acetylated res...

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Detalhes bibliográficos
Main Authors: Liyasova, Mariya S., Schopfer, Lawrence M., Lockridge, Oksana
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812595/
https://ncbi.nlm.nih.gov/pubmed/19836360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.10.007
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