Hepatocyte growth factor (HGF) modulates GABAergic inhibition and seizure susceptibility

Disrupted ontogeny of forebrain inhibitory interneurons leads to neurological disorders, including epilepsy. Adult mice lacking the urokinase plasminogen activator receptor (Plaur) have decreased numbers of neocortical GABAergic interneurons and spontaneous seizures, attributed to a reduction of hep...

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Autores principales: Bae, Mihyun H., Bissonette, Gregory B., Mars, Wendy M., Michalopoulos, George K., Achim, Cristian L., Depireux, Didier A., Powell, Elizabeth M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812579/
https://ncbi.nlm.nih.gov/pubmed/19853606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.10.011
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