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Elevated cutaneous Smad activation associates with enhanced skin tumor susceptibility in organ transplant recipients
PURPOSE: Non-melanoma skin cancer incidence is enhanced over fifty fold in patients taking anti-rejection drugs (ARDs) following organ transplantation. Pre-clinical studies suggest that ARD treatment increases transforming growth factor β1 (TGF-β1) levels, which contribute to enhanced tumor suscepti...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812428/ https://ncbi.nlm.nih.gov/pubmed/19671862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3286 |
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