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A novel subset of memory B cells is enriched in autoreactivity and correlates with adverse outcomes in SLE

We previously reported that some systemic lupus erythematosus (SLE) patients have a population of circulating memory B cells with >2-fold higher levels of CD19. We show here that the presence of CD19(hi) B cells correlates with long-term adverse outcomes. These B cells do not appear anergic, as t...

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Bibliografiske detaljer
Main Authors: Nicholas, Matilda W, Dooley, Mary Anne, Hogan, Susan L., Anolik, Jennifer, Looney, John, Sanz, Ingnacio, Clarke, Stephen H
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812414/
https://ncbi.nlm.nih.gov/pubmed/18077220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2007.10.004
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