SELP and SELPLG Genetic Variation Is Associated with Cell Surface Measures of SELP and SELPLG: The Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study

BACKGROUND: P-selectin (SELP) and its ligand, P-selectin glycoprotein ligand 1 (SELPLG), play key roles in both the inflammatory response and the atherosclerotic process. Previous studies have shown genetic variation in the SELP gene [selectin P (granule membrane protein 140kDa, antigen CD62)] to be...

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Hauptverfasser: Volcik, Kelly A., Catellier, Diane, Folsom, Aaron R., Matijevic, Nena, Wasserman, Bruce, Boerwinkle, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812411/
https://ncbi.nlm.nih.gov/pubmed/19395438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2008.119487
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