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During Lytic Infections, Herpes Simplex Virus Type 1 DNA Is in Complexes with the Properties of Unstable Nucleosomes

The genomes of herpes simplex virus type 1 (HSV-1) are regularly chromatinized during latency such that their digestion with micrococcal nuclease (MCN) releases nucleosome-sized DNA fragments. In lytically infected cells, in contrast, MCN releases HSV-1 DNA in primarily heterogeneously sized fragmen...

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Detalhes bibliográficos
Main Authors: Lacasse, Jonathan J., Schang, Luis M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812404/
https://ncbi.nlm.nih.gov/pubmed/20007274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01934-09
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