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Circularization of the Herpes Simplex Virus Type 1 Genome upon Lytic Infection

For many years, the generally accepted model for the replication of the double-stranded DNA genome of herpes simplex virus type 1 (HSV-1) incorporated initial circularization of linear molecules in the cell nucleus. Ensuing DNA synthesis resulted in the generation of head-to-tail concatemers which w...

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Detalhes bibliográficos
Main Authors: Strang, Blair L., Stow, Nigel D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1211550/
https://ncbi.nlm.nih.gov/pubmed/16160176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.19.12487-12494.2005
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