Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel

The epothilones are naturally occurring, cytotoxic macrolides that function through a paclitaxel (Taxol)-like mechanism. Although structurally dissimilar, both classes of molecules lead to the arrest of cell division and eventual cell death by stabilizing cellular microtubule assemblies. The epothil...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Chou, Ting-Chao, Zhang, Xiu-Guo, Harris, Christina R., Kuduk, Scott D., Balog, Aaron, Savin, Kenneth A., Bertino, Joseph R., Danishefsky, Samuel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC28124/
https://ncbi.nlm.nih.gov/pubmed/9861050
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky