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Cellular Corepressor TLE2 Inhibits Replication-and-Transcription- Activator-Mediated Transactivation and Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus

Replication and transcription activator (RTA) encoded by open reading frame 50 (ORF50) of Kaposi's sarcoma-associated herpesvirus (KSHV) is essential and sufficient to initiate lytic reactivation. RTA activates its target genes through direct binding with high affinity to its responsive element...

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Bibliografiske detaljer
Main Authors: He, Zhiheng, Liu, Yunhua, Liang, Deguang, Wang, Zhuo, Robertson, Erle S., Lan, Ke
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812399/
https://ncbi.nlm.nih.gov/pubmed/19939918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01984-09
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