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Cyclin-Dependent Kinase 1-Mediated Bcl-x(L)/Bcl-2 Phosphorylation Acts as a Functional Link Coupling Mitotic Arrest and Apoptosis

Despite detailed knowledge of the components of the spindle assembly checkpoint, a molecular explanation of how cells die after prolonged spindle checkpoint activation, and thus how microtubule inhibitors and other antimitotic drugs ultimately elicit their lethal effects, has yet to emerge. Mitotica...

詳細記述

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書誌詳細
主要な著者: Terrano, David T., Upreti, Meenakshi, Chambers, Timothy C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812246/
https://ncbi.nlm.nih.gov/pubmed/19917720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00882-09
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