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Genetic Immunization Converts the Trypanosoma cruzi B-Cell Mitogen Proline Racemase to an Effective Immunogen

Trypanosoma cruzi is the etiologic agent of Chagas' disease. Acute T. cruzi infection results in polyclonal B-cell activation and delayed specific humoral immunity. T. cruzi proline racemase (TcPRAC), a T. cruzi B-cell mitogen, may contribute to this dysfunctional humoral response. Stimulation...

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Bibliografske podrobnosti
Main Authors: Bryan, Marianne A., Norris, Karen A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812217/
https://ncbi.nlm.nih.gov/pubmed/19917711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00926-09
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