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Stable Transfection of Trypanosoma cruzi Epimastigotes with the Trypomastigote-Specific Complement Regulatory Protein cDNA Confers Complement Resistance

Trypanosoma cruzi blood stage trypomastigotes are highly resistant to complement-mediated killing in normal serum. A previously described trypomastigote surface glycoprotein was shown to have binding affinity for human complement components C3b and C4b and restrict activation of the complement casca...

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Bibliographic Details
Main Author: Norris, Karen A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108225/
https://ncbi.nlm.nih.gov/pubmed/9596703
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