Randomized, Double-Blind Study of the Safety, Tolerability, and Efficacy of Tafenoquine versus Mefloquine for Malaria Prophylaxis in Nonimmune Subjects

This study represents the first phase III trial of the safety, tolerability, and effectiveness of tafenoquine for malaria prophylaxis. In a randomized (3:1), double-blinded study, Australian soldiers received weekly malaria prophylaxis with 200 mg tafenoquine (492 subjects) or 250 mg mefloquine (162...

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Autores principales: Nasveld, Peter E., Edstein, Michael D., Reid, Mark, Brennan, Leonard, Harris, Ivor E., Kitchener, Scott J., Leggat, Peter A., Pickford, Philip, Kerr, Caron, Ohrt, Colin, Prescott, William
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Clinical Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812156/
https://ncbi.nlm.nih.gov/pubmed/19995933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00354-09
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