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Pharmacokinetics of Itraconazole in Diabetic Rats
After intravenous or oral administration of 10 mg/kg itraconazole to rats with streptozotocin-induced diabetes mellitus and to control rats, the total area under the plasma concentration-time curve from time 0 to 24 h (AUC(0-24)) for itraconazole and that for its metabolite, 7-hydroxyitraconazole, w...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812152/ https://ncbi.nlm.nih.gov/pubmed/19995926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01145-09 |
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