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Dose-Dependent Pharmacokinetics of Itraconazole after Intravenous or Oral Administration to Rats: Intestinal First-Pass Effect

The dose-dependent pharmacokinetics of itraconazole after intravenous (10, 20, or 30 mg/kg) and oral (10, 30, or 50 mg/kg) administration and the first-pass effects of itraconazole after intravenous, intraportal, intragastric, and intraduodenal administration at a dose of 10 mg/kg were evaluated in...

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Detalhes bibliográficos
Main Authors: Shin, Jee H., Choi, Ka Y., Kim, Yu C., Lee, Myung G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400537/
https://ncbi.nlm.nih.gov/pubmed/15105131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1756-1762.2004
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