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Triclosan Resistance of Pseudomonas aeruginosa PAO1 Is Due to FabV, a Triclosan-Resistant Enoyl-Acyl Carrier Protein Reductase

Triclosan, a very widely used biocide, specifically inhibits fatty acid synthesis by inhibition of enoyl-acyl carrier protein (ACP) reductase. Escherichia coli FabI is the prototypical triclosan-sensitive enoyl-ACP reductase, and E. coli is extremely sensitive to the biocide. However, other bacteria...

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Autori principali: Zhu, Lei, Lin, Jinshui, Ma, Jincheng, Cronan, John E., Wang, Haihong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812149/
https://ncbi.nlm.nih.gov/pubmed/19933806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01152-09
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