Chloroquine Modulates HIV-1-Induced Plasmacytoid Dendritic Cell Alpha Interferon: Implication for T-Cell Activation

Plasmacytoid dendritic cells (pDC) contribute to antiviral immunity mainly through recognition of microbial products and viruses via intracellular Toll-like receptor 7 (TLR7) or TLR9, resulting in the production of type I interferons (IFNs). Although interferons reduce the viral burden in the acute...

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Detalhes bibliográficos
Main Authors: Martinson, Jeffrey A., Montoya, Carlos J., Usuga, Xiomara, Ronquillo, Rollie, Landay, Alan L., Desai, Seema N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812138/
https://ncbi.nlm.nih.gov/pubmed/19949061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01246-09
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