Differential Pharmacodynamic Effects of Paclitaxel Formulations in an Intracranial Rat Brain Tumor Model

Nano- and microparticulate carriers can exert a beneficial impact on the pharmacodynamics of anticancer agents. To investigate the relationships between carrier and antitumor pharmacodynamics, paclitaxel incorporated in liposomes (L-pac) was compared with the clinical standard formulated in Cremopho...

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Bibliografiske detaljer
Main Authors: Zhou, Rong, Mazurchuk, Richard V., Tamburlin, Judith H., Harrold, John M., Mager, Donald E., Straubinger, Robert M.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2010
Fag:
Chemotherapy, Antibiotics, and Gene Therapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812113/
https://ncbi.nlm.nih.gov/pubmed/19861574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.160044
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