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All of the human β-type globin genes compete for LCR enhancer activity in embryonic erythroid cells of yeast artificial chromosome transgenic mice
In primitive erythroid cells of human β-globin locus transgenic mice (TgM), the locus control region (LCR)-proximal ε- and γ-globin genes are transcribed, whereas the distal δ- and β-globin genes are silent. It is generally accepted that the β-globin gene is competitively suppressed by γ-globin gene...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Federation of American Societies for Experimental Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812047/ https://ncbi.nlm.nih.gov/pubmed/19690216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-137778 |
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