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Functional Delivery of a Membrane Protein into Oocyte Membranes Using Bicelles,

The voltage-gated potassium channel modulatory membrane protein KCNE3 was overexpressed and purified into both micelles and bicelles. Remarkably, microinjection of KCNE3 in bicelles into Xenopus oocytes resulted in functional co-assembly with the human KCNQ1 channel expressed therein. Microinjection...

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Detalhes bibliográficos
Main Authors: Kang, Congbao, Vanoye, Carlos G., Welch, Richard C., Van Horn, Wade D., Sanders, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811756/
https://ncbi.nlm.nih.gov/pubmed/20044833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902155t
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