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Phospholipase C Gamma 2 Is Critical for Development of a Murine Model of Inflammatory Arthritis by Affecting Actin Dynamics in Dendritic Cells

BACKGROUND: Dendritic cells (DCs) are highly specialized cells, which capture antigen in peripheral tissues and migrate to lymph nodes, where they dynamically interact with and activate T cells. Both migration and formation of DC-T cell contacts depend on cytoskeleton plasticity. However, the molecu...

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Bibliografiske detaljer
Main Authors: Cremasco, Viviana, Benasciutti, Elisa, Cella, Marina, Kisseleva, Marina, Croke, Monica, Faccio, Roberta
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811739/
https://ncbi.nlm.nih.gov/pubmed/20111715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008909
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