Anti-Argonaute RIP-Chip shows that miRNA transfections alter global patterns of mRNA recruitment to microribonucleoprotein complexes

MicroRNAs (miRNAs) play key roles in gene expression regulation by guiding Argonaute (AGO)-containing microribonucleoprotein (miRNP) effector complexes to target polynucleotides. There are still uncertainties about how miRNAs interact with mRNAs. Here we employed a biochemical approach to isolate AG...

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Hlavní autoři: Wang, Wang-Xia, Wilfred, Bernard R., Hu, Yanling, Stromberg, Arnold J., Nelson, Peter T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811668/
https://ncbi.nlm.nih.gov/pubmed/20042474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1905910
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