Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53

MicroRNAs (miRNAs) regulate the expression of multiple proteins in a dose dependent manner. We hypothesized that increased expression of miRNAs encoded on chromosome 21 (chr 21) contribute to the leukemogenic role of trisomy 21. The levels of chr 21 miRNAs were quantified by qRT-PCR in four types of...

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Autori principali: Gefen, Nir, Binder, Vera, Zaliova, Marketa, Linka, Yvonne, Morrow, Michelle, Novosel, Astrid, Edry, Liat, Hertzberg, Libi, Shomron, Noam, Williams, Owen, Trka, Jan, Borkhardt, Arndt, Izraeli, Shai
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811577/
https://ncbi.nlm.nih.gov/pubmed/19890372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.208
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