Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53

MicroRNAs (miRNAs) regulate the expression of multiple proteins in a dose dependent manner. We hypothesized that increased expression of miRNAs encoded on chromosome 21 (chr 21) contribute to the leukemogenic role of trisomy 21. The levels of chr 21 miRNAs were quantified by qRT-PCR in four types of...

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Detalhes bibliográficos
Main Authors: Gefen, Nir, Binder, Vera, Zaliova, Marketa, Linka, Yvonne, Morrow, Michelle, Novosel, Astrid, Edry, Liat, Hertzberg, Libi, Shomron, Noam, Williams, Owen, Trka, Jan, Borkhardt, Arndt, Izraeli, Shai
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811577/
https://ncbi.nlm.nih.gov/pubmed/19890372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.208
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