An effector role for platelets in systemic and local lipopolysaccharide-induced toxicity in mice, mediated by a CD11a- and CD54-dependent interaction with endothelium.

The role of platelets was investigated in two models of lipopolysaccharide (LPS)-induced toxicity in mice: the systemic reaction, provoked by intravenous LPS injection in D-galactosamine-sensitized recipients, which results in host death, and the local reaction, elicited in the skin by sequential in...

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Udgivet i:Infect Immun
Main Authors: Piguet, P F, Vesin, C, Ryser, J E, Senaldi, G, Grau, G E, Tacchini-Cottier, F
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8104895/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.10.4182-4187.1993
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